The two main generals who commanded the opposing forces at the Battle of Gettysburg were General George Meade of the Union Army and General Robert E. Lee of the Confederate Army.

Meade took command of the Union forces just days before the battle, leading them to a decisive victory. Lee, aiming to secure a significant victory on Northern soil, launched an offensive that ultimately failed. Their leadership styles and decisions during the battle played crucial roles in shaping the outcome, marking Gettysburg as a turning point in the Civil War.