Catfish is the most commonly farmed species in U.S. aquaculture, particularly in the southeastern states.

Catfish farming dominates U.S. aquaculture due to its efficiency and high consumer demand. The channel catfish is the primary species raised, with states like Mississippi, Alabama, and Arkansas leading production. These regions have ideal conditions, including warm climates and abundant freshwater resources, for pond-based farming. Catfish farming is known for its sustainable practices, providing a reliable protein source while reducing pressure on wild fish stocks. The industry's growth has made catfish a staple in U.S. cuisine, especially in Southern dishes, contributing significantly to both local economies and the nation's seafood market.