Ulysses S. Grant is the president known for having a deep personal connection to the Mississippi River.

Ulysses S. Grant, the 18th president of the United States, had a profound personal connection to the Mississippi River, stemming from his experiences as a young man and a military leader. Growing up in Ohio and later serving in the Civil War, Grant recognized the river's strategic importance. His leadership during the Siege of Vicksburg in 1863, a key battle along the river, solidified his legacy and highlighted the river's critical role in American history and commerce.