A major challenge for farming in the Interior Plains is soil erosion.

While the region has fertile soils that are excellent for agriculture, practices such as intensive farming, deforestation, and improper land management can lead to erosion. This process can strip away the nutrient-rich topsoil, making it difficult to maintain crop yields. Additionally, the flat terrain of the Interior Plains makes the area susceptible to wind and water erosion, further complicating farming efforts. Farmers in the region often implement conservation techniques to mitigate soil loss and sustain agricultural productivity.