Milwaukee is not located directly on the Mississippi River; it lies on the shores of Lake Michigan.

Milwaukee is not situated along the Mississippi River but instead lies on the western shore of Lake Michigan, part of the Great Lakes system. While cities like Davenport, Memphis, and Baton Rouge are directly on the Mississippi River, Milwaukee is located much further north. Its waterfront, however, offers its own significant historical and economic importance, with a focus on shipping and tourism related to the Great Lakes.