The natural feature that is the result of glacial activity in the Appalachian region is Valleys.

Glacial activity during the last Ice Age carved out many of the valleys found in the Appalachian Mountains. As glaciers advanced and retreated, they shaped the landscape by deepening and widening existing valleys and creating new ones. This process led to the formation of U-shaped valleys, which are characteristic of glaciated regions. These glacially-formed valleys contribute to the unique topography and hydrology of the Appalachian region, influencing the area's ecology and human settlement patterns.