Chicago is a major U.S. city located at the mouth of the Chicago River, where it flows into Lake Michigan.

Chicago, the third-largest city in the U.S., is located at the mouth of the Chicago River, where it empties into Lake Michigan. This strategic location has made Chicago a major hub for trade, transportation, and industry, especially during the 19th and 20th centuries. The city's waterfront is iconic, with a skyline that includes famous landmarks such as the Willis Tower and Navy Pier. The river itself has played a key role in the city's development, and the unique engineering feat of reversing its flow in the early 20th century helped control pollution and improve water quality.