The South was the region most affected by battles during the American Civil War.

Many key conflicts, such as the Battle of Gettysburg and the Siege of Vicksburg, occurred in southern states like Virginia, Georgia, and Mississippi. The war left much of the South devastated, with cities, farmlands, and infrastructure destroyed. Economically, the region suffered immense losses, especially with the collapse of its slavery-based economy. The aftermath of the Civil War led to long-term challenges for the South, including Reconstruction, economic hardship, and social upheaval, as it struggled to rebuild and recover from the widespread destruction.