The Interior Plains are primarily covered by grasslands.

This vast region is characterized by its expansive prairies, where grasses dominate the landscape, providing habitat for a variety of wildlife. The northern areas feature mixed-grass prairies, while the southern regions are home to tallgrass prairies. These grasslands are vital for agriculture, particularly for grazing livestock and growing crops such as wheat and corn. The rich soil and favorable climate conditions contribute to the productivity of these grasslands, making the Interior Plains a key agricultural area in North America.