The typical weather patterns in the Interior Plains are highly variable, with hot summers and cold winters.

This region experiences a continental climate, characterized by significant temperature fluctuations throughout the year. In summer, temperatures can rise significantly, leading to hot and often humid conditions, while winter brings cold temperatures and the possibility of snow. The area is also prone to severe weather events, including thunderstorms and tornadoes, particularly in the spring and summer months. This variability in weather plays a crucial role in shaping the landscape and agricultural practices of the Interior Plains.