Roanoke, located in the heart of the Blue Ridge Mountains, is the largest city near the Appalachian Mountains in Virginia.

Roanoke, often referred to as the "Star City of the South," is situated in southwestern Virginia and serves as a gateway to the Appalachian region. It is well-known for its scenic beauty, outdoor activities, and its position along the Blue Ridge Parkway. The city has a rich history tied to railroads, earning it the nickname "Magic City" during its rapid growth in the late 19th century. Today, Roanoke is a hub for cultural events, economic activity, and outdoor recreation in the Appalachian area of Virginia. Other cities like Richmond and Norfolk are farther east and not directly associated with the Appalachian region.