The Great Basin is primarily known for its dry, arid, and semi-arid climate.

The Great Basin is characterized by its lack of consistent rainfall, making it an arid and semi-arid region. The climate is marked by low precipitation, with many areas receiving less than 10 inches of rain annually. These dry conditions support desert and scrub vegetation, and the ecosystem is adapted to withstand these harsh conditions. The region's topography, including mountain ranges, valleys, and salt flats, further contributes to the overall dryness, making it a distinctive feature of the Great Basin.