The total estimated number of casualties at the Battle of Gettysburg was 50,000.

This figure encompasses the total number of killed and wounded soldiers from both the Union and Confederate forces, marking it as one of the most brutal battles of the American Civil War. The Union experienced roughly 23,000 casualties, while the Confederates endured about 28,000. The immense loss of life and injuries underscored the battle's ferocity and the severe impact it had on both sides, profoundly influencing the trajectory of the war and shaping public opinion in both the North and South.