Las Vegas, Nevada, is the largest urban center by population within the Mojave Desert, known for its vibrant entertainment and tourism industry.

Las Vegas, located in the northeastern part of the Mojave Desert, is the most populous city in the region, with over 600,000 residents and a metropolitan area exceeding 2 million people. Its rapid growth stems from its status as a global entertainment hub, renowned for casinos, resorts, and nightlife. The city thrives despite its desert environment, relying on extensive water management systems and energy resources. While Palm Springs, San Bernardino, and Barstow are also located near or within the Mojave, they are significantly smaller in population and economic scale compared to Las Vegas.