The Mississippi River is part of North America's largest drainage basin.

The Mississippi River is an integral part of North America’s largest drainage basin, known as the Mississippi River Basin. This vast area spans approximately 1.2 million square miles, draining water from over 31 U.S. states and parts of Canada. The basin is crucial for agriculture, ecosystem health, and water management, significantly impacting the economy and environment of the central United States. It plays a vital role in sustaining diverse wildlife and natural resources.