The initiative launched in the 1960s to reduce poverty and promote development in the Appalachian region is The Appalachian Regional Commission.

Formed in 1965, the Appalachian Regional Commission (ARC) aimed to address the economic challenges faced by the Appalachian region. By fostering partnerships among federal, state, and local governments, the ARC focused on improving infrastructure, education, healthcare, and economic development. This initiative has played a crucial role in transforming the Appalachian economy and enhancing the quality of life for its residents.