Besides coal, natural gas is also extracted from the Appalachian Mountains.

The region, particularly in areas like West Virginia and Pennsylvania, has significant natural gas reserves, especially in the Marcellus Shale formation. The extraction of natural gas has become increasingly important in recent years due to advancements in drilling technologies, such as hydraulic fracturing (fracking). This resource has contributed to the local economy and energy production, although it has also raised environmental concerns related to water usage, air quality, and land disruption.