The infamous Hatfield-McCoy feud took place in the Appalachian region along the border between Kentucky and West Virginia.

This family conflict, which lasted from the 1860s to the 1890s, became one of the most well-known feuds in American history. The dispute between the Hatfields of West Virginia and the McCoys of Kentucky involved issues like land, politics, and personal grievances, and it escalated into violence between the two families. The feud has since become a symbol of the fierce independence and familial loyalty associated with Appalachian culture.